ro25 6981 (Tocris)

Tocris is a verified supplier

Tocris manufactures this product

About

News

Press Release

Team

Advisors

Partners

Contact

Bioz Stars

Bioz vStars

Buy from Supplier

Structured Review

Tocris ro25 6981
Ro25 6981, supplied by Tocris, used in various techniques. Bioz Stars score: 93/100, based on 198 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/ro25+6981/TL+0259/pm41052993-131-22-23
Average 93 stars, based on 198 article reviews

ro25 6981 - by Bioz Stars, 2026-09

93/100 stars

Images

other:

Article Title: Prefrontal cortical NR2B-containing NMDA receptors are essential for spatial working memory performance
Article Snippet: The monkeys received bilateral intracranial infusions of 3 μl drug solution which included 7.5 μg muscimol (Sigma Chemical, USA) or 15 μg Ro25-6981 (Tocris, UK) at each cannula.

Article Title: Non-ionotropic signaling through the NMDA receptor GluN2B carboxy-terminal domain drives dendritic spine plasticity and reverses fragile X phenotypes
Article Snippet: Ro25-6981 , Tocris , 1594.

Article Title: Alleviation of migraine related pain and anxiety by inhibiting calcium-stimulating AC1-dependent CGRP in the insula of adult rats.
Article Snippet: PEAQX (3 μM, Tocris, UK) was used as GluN2A receptor inhibitor and Ro25-6981 (3 μM, Tocris, UK) was used as GluN2B receptor.

Article Title: Alleviation of migraine related pain and anxiety by inhibiting calcium-stimulating AC1-dependent CGRP in the insula of adult rats
Article Snippet: PEAQX (3 μM, Tocris, UK) was used as GluN2A receptor inhibitor and Ro25-6981 (3 μM, Tocris, UK) was used as GluN2B receptor.

Article Title: Prefrontal cortical NR2B-containing NMDA receptors are essential for spatial working memory performance.
Article Snippet: The monkeys received bilateral intracranial infusions of 3 μl drug solution which included 7.5 μg muscimol (Sigma Chemical, USA) or 15 μg Ro25-6981 (Tocris, UK) at each cannula.

Saline:

Article Title: Prefrontal Cortical NR2B-Containing NMDA Receptors are Essential for Spatial Working Memory Performance
Article Snippet: .. Animals received bilateral intracranial infusions of either 0 (saline) or 7.5 µg muscimol (Sigma Chemical, USA) or 15µg Ro25-6981 (Tocris, UK) in 3 µl saline for each cannula. .. Infusion was driven by a microsyringe pump (Bioanalytical System Inc., West Lafayette, IN, USA) using 5 µl microsyringes at a speed of 1 µl/min.

Recombinant:

Article Title: Hevin/Sparcl1 drives pathological pain through spinal cord astrocyte and NMDA receptor signaling
Article Snippet: .. We purchased formalin, carrageenan, CFA, and NMDA from Sigma-Aldrich; TCN201 (GluN2A antagonist; catalog 4154) and RO25-6981 (GluN2B antagonist; catalog 1594) from Tocris; and recombinant hevin from R&D Systems (catalog 4547-SL). ..

Clinical Proteomics:

Article Title: Prelimbic proBDNF Facilitates Retrieval-Dependent Fear Memory Destabilization by Regulation of Synaptic and Neural Functions in Juvenile Rats.
Article Snippet: Fear regulation changes as a function of the early life is a key developmental period for the continued maturation of fear neural circuitry.. The mechanisms of fear retrieval-induced reconsolidation have been investigated but remain poorly understood.. The involvement of prelimbic proBDNF in fear memory extinction and its mediated signaling have been reported previously.

Review